Sprout - Methodology

Our Methodology

Sprout uses a transparent, evidence-based approach to generate personalised supplement recommendations. Here's how it works.

Evidence Levels

Each supplement in our database is assigned an evidence level based on the quality and quantity of research supporting its use:

High

Strong Research Support

Multiple RCTs or meta-analyses confirm efficacy. Consistent results across diverse populations.

Moderate

Promising Evidence

Some RCTs or observational studies support use. Results may vary across populations.

Low

Early Stage Research

Limited human studies or conflicting results. Insufficient clinical evidence at this time.

Data Sources

Our supplement database is built from peer-reviewed research, primarily sourced from:

PubMed / MEDLINE: Primary source for clinical studies and systematic reviews
Cochrane Reviews: Gold-standard systematic reviews and meta-analyses
NIH Office of Dietary Supplements: Comprehensive fact sheets on supplement safety and efficacy
Examine.com: Independent supplement research aggregator (for reference)

Recommendation Engine

Our recommendation engine uses a deterministic, rules-based approach:

1

Goal Matching

Each supplement is tagged with the health goals it supports. When you select your goals, we match you with supplements that have evidence for those specific outcomes.

2

Diet Adjustments

Plant-based diets have different nutritional needs. We automatically prioritise B12 and iron for vegetarians and vegans, as these are harder to obtain without animal products.

3

Interaction Analysis

We flag supplements that should be taken together for synergy (e.g. Vitamin D + K2) or separated for optimal absorption (e.g. iron and zinc).

4

Timing Optimisation

Each supplement has an optimal time of day based on pharmacokinetics, whether it needs food, and potential effects on sleep or energy.

Limitations

Not medical advice. This tool is educational only. It cannot diagnose conditions or replace professional medical guidance.

No drug interactions. We do not account for supplement–drug interactions. If you take medications, consult your doctor or pharmacist.

Individual variation. Research results are population averages. Your personal response may differ based on genetics, health status, and other factors.

Curated dataset. Our database includes commonly studied supplements but is not exhaustive. Absence from our list doesn't mean a supplement lacks merit.

Safety First

Important Safety Information

Always consult a healthcare provider before starting any supplement regimen, especially if you are pregnant, nursing, have a medical condition, or take medications.

Do not exceed recommended dosages. More is not always better and can be harmful.

If you experience adverse effects, discontinue use and seek medical attention.

Supplements are not evaluated by the FDA for safety and efficacy before marketing.